NADH, or reduced nicotinamide adenine dinucleotide , is a chemical made in your body from niacin, a type of B vitamin. NADH helps your body make energy. Some people take it in supplement form to treat chronic fatigue syndrome (also known as myalgic encephalomyelitis or ME/CFS ). NADH's role in cellular respiration takes place with the electron transport chain. NADH is the junction of nicotinamide adenine dinucleotide (NAD+) and hydrogen. Thus, it is the reduced form of Found in all living cells, NAD is called a dinucleotide because it consists of two nucleotidesjoined through their phosphategroups. One nucleotide contains an adeninenucleobaseand the other, nicotinamide. NAD exists in two forms: an oxidized and reducedform, abbreviated as NAD+and NADH(H for hydrogen), respectively. Nicotinamide adenine dinucleotide (NAD+) is an essential coenzyme involved in several redox reactions. NAD + also serves as an important substrate for several enzymes associated with DNA repair, secondary messenger signaling, and transcriptional regulation. Dosing Reviews (40) Overview NADH stands for "nicotinamide adenine dinucleotide (NAD) + hydrogen (H)." It occurs naturally in the body and plays a role in generating energy. The NADH produced VSc9WP.